Effective May 1, 2026, Excalia® Fungicide (inpyrfluxam) has been approved for use in tobacco under a Section 18 emergency exemption to manage target spot in North Carolina. This approval allows growers to incorporate Excalia into a fungicide rotation to help manage target spot and slow emerging azoxystrobin resistance.

Growers must follow all use instructions associated with this exemption. A copy of the Section 18 label must be in their possession during mixing and application, and pesticide application records must document any use of Excalia during the exemption period.

Section 18 Emergency Exemption Label
NC Excalia Tobacco Target Spot Sec-18 Label

Resources

• 2025 Fungicide Programs for Target Spot in NC Flue-Cured Tobacco
  • Excalia and Quadris Flowable Rotations significantly reduced disease
• 2024 Fungicide Programs for Target Spot in NC Flue-Cured Tobacco
  • Manzate Pro-Stick and Quadris Flowable Rotations
• Target Spot Factsheet